A cikin yaƙi da cutar a farkon 2020, a cikin kwanaki 35 kacal, an kafa samfurin linzamin kwamfuta na ACE2 na ɗan adam, kuma mai bincike Guangming Wu da takwarorinsa daga Cibiyar Nazarin Fate da Lantarki (CCLA) a dakunan gwaje-gwaje na Bio-Island sun yi nasarar yin nasara. babban ci gaba ta hanyar amfani da fasaha na kwayar halitta don ƙirƙirar "yaki da Sabon Cutar Pneumonia".Abin al'ajabi na sauri a cikin harin gaggawa.
Gwaji kwatsam
A watan Agustan shekarar 2019, Wu Guangming, wanda ya dade yana bincike a fannin ci gaban haihuwa, ya dawo birnin Guangzhou daga kasar Jamus, inda ya shiga rukunin farko na "Lardin Guangdong don gina tawagar dakin gwaje-gwaje ta kasa" na dakin gwaje-gwaje na Bio-Island, wato dakin gwaje-gwaje na Magungunan Farfaɗo da Lafiya na Guangzhou Guangdong.
Abin da bai yi tsammani ba shi ne cewa ba za a dade ba kafin ya fuskanci gwajin ba-zata na sabon kambin cutar huhu.
“Babban binciken da na tsunduma a a zahiri ba shi da alaka da cututtuka masu yaduwa, sai dai ta fuskar bullar annobar da ke tafe, bayan da ta samu labarin cewa ma’aikatar kimiyya da fasaha ta lardin Guangdong ta kafa wani shiri na musamman na binciken gaggawa kan sabon kambin. annobar cutar huhu, na yi mamakin abin da zan iya yi don yakar cutar a lokacin da kasar baki daya ke aiki tare."
Ta hanyar fahimta, Wu Guangming ya gano cewa ana buƙatar nau'ikan dabbobin da aka ƙera cikin gaggawa don ganowa da kuma kula da sabon coronavirus da kuma sarrafa shi na dogon lokaci.Abin da ake kira samfurin dabbar ɗan adam shine yin dabbobi (birai, beraye, da dai sauransu) tare da wasu halaye na kyallen jikin mutum, gabobin jiki, da kwayoyin halitta ta hanyar gyaran kwayoyin halitta da sauran hanyoyin da za a gina nau'in cututtuka, nazarin hanyoyin cututtuka na cututtuka na mutum da ganowa. mafita mafi kyawun magani.
An kammala harin cikin kwanaki 35
Wu Guangming ya shaidawa manema labarai cewa, a wancan lokacin akwai nau'ikan kwayoyin halitta na in vitro, kuma mutane da yawa sun damu.Ya kasance yana da shekaru masu yawa na gwaninta a binciken dabbar transgenic kuma yana da kyau a fasahar diyya ta tetraploid.Ɗaya daga cikin ra'ayoyin bincikensa a baya shi ne haɗa fasahar zamani ta embryonic da fasaha na tetraploid na amfrayo tare don kafa nau'in linzamin kwamfuta na ɗan adam, kuma yana ƙarfafawa cewa Cibiyar Nazarin Fate da Genealogy a Bio Island Laboratories sannan tana da jagorancin fasahar kwayar halitta. , kuma ga alama duk yanayin waje sun cika.
Tunani abu daya ne, yin wani abu kuma.
Yaya wahalar gina ƙirar linzamin kwamfuta mai amfani?A karkashin tsarin al'ada, zai ɗauki aƙalla watanni shida kuma ya wuce ta hanyoyin gwaji da kuskure marasa adadi.Amma yayin fuskantar annoba ta gaggawa, mutum yana buƙatar yin tsere da lokaci kuma ya rataya akan taswira.
An kafa tawagar ne bisa ka'ida saboda yawancin mutanen sun riga sun tafi gida don sabuwar shekara ta kasar Sin.A ƙarshe, an gano mutane takwas da suka rage a Guangzhou a ƙarƙashin Cibiyar Nazarin Ƙaddamar Halittu da Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararrun Ƙwararru.
Daga zane na yarjejeniyar gwaji a ranar 31 ga Janairu zuwa haihuwar ƙarni na farko na berayen da aka yi wa ɗan adam a ranar 6 ga Maris, ƙungiyar ta cim ma wannan mu'ujiza ta binciken kimiyya a cikin kwanaki 35 kacal.Fasaha ta al'ada tana buƙatar haɗa ƙwayoyin jikin linzamin kwamfuta da embryos don samun berayen chimeric, kuma kawai lokacin da sel ɗin ya bambanta zuwa ƙwayoyin ƙwayoyin cuta sannan kuma su haɗa tare da wasu beraye don ƙaddamar da ƙwayoyin halittar da aka gyara zuwa tsarar beraye na gaba za a iya ɗaukar su cikin nasara.An haifi berayen da aka yi wa ɗan adam daga CCLA don samun ƙwanƙwasa ƙwanƙwasa a lokaci ɗaya, suna samun lokaci mai mahimmanci da ceton ma'aikata da albarkatun ƙasa don rigakafin annoba.
Wu Guangming a wurin aiki Hoto/wanda aka yi hira da shi ya bayar
Duk aiki overtime
Wu Guangming ya yarda cewa, a farkon, babu wanda zuciyarsa ke da kasa, kuma fasahar tetraploid kanta tana da matukar wahala, inda aka samu nasarar kasa da kashi 2%.
A wancan lokacin, duk mutane sun himmatu wajen gudanar da bincike ba tare da la’akari da rana da rana ba, ba tare da ranakun aiki da kuma karshen mako ba.Kowace rana da ƙarfe 3:00 ko 4:00 na safe, ’yan ƙungiyar sun tattauna ci gaban ranar;Suna ta hira har gari ya waye, nan take suka koma wani ranar bincike.
A matsayinsa na shugaban fasaha na tawagar binciken, Wu Guangming ya daidaita bangarori biyu na aiki - gyaran kwayoyin halitta da al'adun mahaifa - sannan ya bi kowane mataki na tsarin gwaji da warware matsalolin cikin lokaci, wanda ya fi damuwa fiye da yadda mutum zai iya. tunanin.
A lokacin, saboda hutun bikin bazara da annoba, duk abubuwan da ake buƙata sun ƙare, kuma dole ne mu sami mutane a ko'ina don aro su.Ayyukan yau da kullun shine gwaji, gwaji, aika samfurori da neman masu sakewa.
Domin gaggawar lokacin, ƙungiyar bincike ta karya yanayin al'ada na tsarin gwaji, yayin da farkon shirye-shiryen kowane mataki na gwaji na gaba.Amma wannan kuma yana nufin cewa idan wani abu ya ɓace a cikin matakan da suka gabata, an shirya matakan da suka biyo baya a banza.
Koyaya, gwaje-gwajen halittu da kansu wani tsari ne da ke buƙatar gwaji da kuskure akai-akai.
Wu Guangming ya tuna cewa sau ɗaya, an yi amfani da in vitro vector don sakawa cikin jerin DNA ta salula, amma hakan bai yi tasiri ba, don haka dole ne ya daidaita ma'aunin reagent da sauran sigogi akai-akai kuma ya sake maimaita shi har sai ya zama. aiki.
Aiki ya tada hankalin kowa ya yi yawa, wasu 'yan uwa akwai kumbura a bakinsu, wasu kuma sun gaji sai kawai suka tsugunna a kasa suna magana saboda sun kasa tashi.
Don samun nasara, Wu Guangming, har ma ya ce ya yi sa'a ya gana da gungun kwararrun takwarorinsu, kuma yana da kyau a kammala aikin gina samfurin linzamin kwamfuta cikin kankanin lokaci.
Har yanzu ana son kara ingantawa
A ranar 6 ga Maris, an sami nasarar haihuwar berayen ƙarni na farko na ɗan adam.Koyaya, ana iya bayyana wannan a matsayin matakin farko na kammala aikin, wanda cikin sauri ya biyo bayan tsauraran matakan tabbatarwa da aika ɓerayen ɗan adam zuwa dakin gwaje-gwaje na P3 don nasarar gwajin ƙwayar cuta.
Koyaya, Wu Guangming ya kuma yi tunanin ƙarin haɓakawa ga ƙirar linzamin kwamfuta.
Ya gaya wa manema labarai cewa kashi 80% na marasa lafiya da ke da COVID-19 suna da asymptomatic ko kuma marasa lafiya, ma'ana za su iya dogaro da nasu rigakafi don murmurewa, yayin da sauran kashi 20% na marasa lafiya suna kamuwa da cuta mai tsanani, galibi a cikin tsofaffi ko waɗanda ke da cututtukan da ke da alaƙa. .Sabili da haka, don yin amfani da ƙirar linzamin kwamfuta daidai da inganci don ilimin cututtuka, magani, da bincike na rigakafi, ƙungiyar tana yin niyya ga berayen da ba su daɗe ba tare da tsufa, ciwon sukari, hauhawar jini, da sauran samfuran cututtukan da ke cikin tushe don kafa ƙirar linzamin kwamfuta mai tsanani.
Da yake waiwaya kan wannan gagarumin aikin, Wu Guangming ya ce, yana alfahari da irin wannan tawaga, inda kowa ya fahimci mahimmancin abin da yake yi, da sanin ya kamata, tare da yin aiki tukuru don cimma irin wannan sakamako.
Hanyoyin haɗi na labarai masu dangantaka:"Annobar Yakin Guangdong Don Girmama Jarumai" Kungiyar Wu Guangming: kwanaki 35 don kafa samfurin linzamin kwamfuta na ACE2 (baidu.com)
Lokacin aikawa: Agusta-02-2023