Cikakken Bayani

Tags samfurin

Quickmice™ Fast KI Mouse Keɓancewa

saurin mice-sauri-ki- linzamin kwamfuta-na gyara-samfurin

Knock-in (Knock-in, KI) wata dabara ce da ke yin amfani da haɗe-haɗe na kwayoyin halitta don canja wurin wani abu mai aiki na waje zuwa jerin homologous a cikin tantanin halitta da kwayoyin halitta, da samun magana da kyau a cikin tantanin halitta bayan sake haɗewar kwayoyin halitta.

Yana ɗaukar watanni 5-6 don samun Neo-deleted heterozygous mice da jimlar watanni 10-12 don gina nau'ikan linzamin kwamfuta na KI homozygous tare da ƙarancin nasara ta amfani da dabarun gargajiya, saboda waɗannan fasahohin suna da ƙarancin ƙimar chimera kuma suna buƙatar mating tare da linzamin kwamfuta zuwa. sami berayen heterozygous da aka goge, sannan kuma kiwo da berayen heterozygous da aka haifa na tsararraki 2-3 don samun mice KI masu homozygous.

Sabuwar ƙarni na Fasahar Shirya Mouse Mai Sauri

TurboMice™

Za mu iya ba ku da sauri samfuran linzamin kwamfuta na KI homozygous ta amfani da fasahar TurboMice™ don haɓaka ƙimar nasara.

Dangane da mafi kyawun shirin gyaran kwayoyin halitta na masana kimiyya, za mu iya kammala tantance gyare-gyaren ƙwanƙwaran ƙwayar mahaifa a cikin kwanaki 3-5, sannan mu gina amfrayo tetraploid.Bayan mahaifar mahaifa, ana iya samun mice ɗin ɗan adam na homozygous a cikin watanni 2-4, wanda zai iya adana watanni 7-8 ga abokan ciniki.

Abubuwan Sabis

Sabis No. Fihirisar fasaha Abun bayarwa Zagayen bayarwa
Saukewa: MC002-1 tsawon kwayar halitta guda <5kb 3-9 KI mice maza masu homozygous Watanni 2-4
Saukewa: MC002-2 tsawon kwayar halitta guda <5kb 10-19 KI mice maza masu homozygous Watanni 2-4
Saukewa: MC002-3 tsawon kwayar halitta guda <5kb 20 KI mice maza masu homozygous Watanni 3-5
Saukewa: MC002-4 Tsawon kwayar halitta guda daya shine 5kb-10kb 3-9 KI mice maza masu homozygous Watanni 3-4
Saukewa: MC002-5 Tsawon kwayar halitta guda daya shine 5kb-10kb 10-19 KI mice maza masu homozygous Watanni 3-4
Saukewa: MC002-6 Tsawon kwayar halitta guda daya shine 5kb-10kb 20 KI mice maza masu homozygous Watanni 3-5

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